Carbomer Cancer. 2023, the US FDA released guidance on benzene-grade carbome

2023, the US FDA released guidance on benzene-grade carbomer formulations, which triggered pharmaceutical manufacturers to assess risk, test finished products, and reformulate drug products with benze … Dec 3, 2025 · FDA has recommended the United States Pharmacopeia (USP) remove (or “omit”) certain carbomer monographs from their compendium that allow for unacceptable levels of benzene (a USP monograph is Feb 6, 2024 · FDA issues guidance on reformulating drug products containing carbomers with benzene to address contamination concerns and ensure pharmaceutical safety. Carbomers are synthetic ingredients that cosmetic and pharmaceutical companies use in products due to their suspending, emulsifying, and thickening properties. Some generic versions use a more cost-effective powder that contains benzene unlike the name-brand cold medicine. In Dec. Carbomer is a group of synthetic high molecular weight polymers of acrylic acid used in cosmetics and skincare products as thickening agents. Chemotherapy by topical application is an attractive strategy because of the ease of application and non-invasiveness. The extent of swelling in carbomers in an aqueous medium depends upon various factors Clinical studies with carbomers showed that these polymers have low potential for skin irritation and sensitization at concentrations up to 100%. Jan 11, 2024 · According to the FDA, carbomers manufactured with benzene that are used in FDA-regulated drug products may fall under the United States Pharmacopeia-National Formulary (USP-NF) monographs Carbomer 934, Carbomer 934P, Carbomer 940, Carbomer 941, or Carbomer 1342. %, solutions exhibit a viscous Newtonian behavior; (ii) at intermediate concentration a visco-elastic shear thinning behavior is activated; and (iii) at higher Overall, carbomers are a useful ingredient in hand hygiene products, helping to improve their texture, consistency, and effectiveness. 555 13th Street, NW, Suite 300W Washington, D.